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Rapp, Bastian E; Dalton, Colin (Ed.)This study presents the development of a highly sensitive microfluidic-based impedance biosensor designed for rapid detection and identification of Salmonella Infantis in raw turkey samples, with a limit of detection (LOD) as low as 1 CFU/ml in 70 minutes detection time. The biosensor is equipped with novel focusing and trapping regions, significantly enhancing its sensitivity by concentrating and trapping Salmonella cells in the detection region. Salmonella cells labeled with fluorescent dyes were used to validate the functionality of the focusing and trapping mechanism, confirming the biosensor's ability to concentrate and trap Salmonella cells.more » « lessFree, publicly-accessible full text available March 20, 2026
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Abuhelwa, Mai; Chenggeer, Fnu; Bandara, Adheesha; Liu, Jiayu; Willoughby, Paige; Carlson, Anna; Trout, Kate; Morey, Amit; Kinzel, Ed; Mustapha, Azlin; et al (, SPIE)Gannot, Israel; Roodenko, Katy (Ed.)This study validates a fiber optics-based Surface Enhanced Raman Spectroscopy (SERS) sensor for detecting Salmonella in raw turkey samples. The sensor uses nanoantenna arrays on a side-polished optical fiber core with a fixed periodicity of 0.77 µm to maximize the SERS signal intensity. A 3D-printed chamber and microstructure optimize light reflection, improving sensitivity. The sensor detects Salmonella at 0.4-0.5 CFU/ml in 10 minutes, offering cost-effective, portable pathogen detection.more » « lessFree, publicly-accessible full text available March 20, 2026
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